Efeitos da dieta e do exercício contrarresistência em parâmetros do perfil lipídico e estresse oxidativo em modelo animal.

Abstract

Obesity has been changing into public health concern, and people believe that it was caused by sedentary behavior, a high fat percentage diet and genetic mutation. It is clear in specialized literature that the regular practice of physical aerobic exercises has a positive hole in obesity control and treatment, both in weight and lipid profile parameters; while the resistance training (RT) benefits on the lipid profile and oxidative stress parameters still require further investigation. This study aimed to evaluate diet and resistance training on the lipid profile and oxidative stress parameters effects on animals. The experimental protocol lasted 12 weeks, and all the animals received a high-fat diet on the first 4 weeks. On the 8 following weeks, the animals were subdivided into four distinct groups, receiving a normal or high-fat diet with or without resistance training. The euthanasia was made at the end of the 12th week to collect tissues (blood and gastrocnemius muscle) and organs (liver). Differences were found on the weight gain and on the dietary and energetic consumption between the groups. The RT load also presented differences between the trained groups. Biochemical dosages (serum, liver and muscle strength) were made, evaluating the lipid profile parameters (total hepatic and muscular fat, total cholesterol, HDL-cholesterol and LDL-cholesterol) and the oxidative stress (TBARS, total Tiol and protein carbonyls). It was found differences on the hepatic analysis at the first parameter and serum, hepatic and muscular differences at the second parameter. From the analysis made, we can conclude that the diet s quantitative lipid alteration results in negative alterations on the hepatic lipid profile and on the serum, hepatic and muscular oxidative stress at the sedentary groups; and the resistance training has positive effects at the same parameters at the trained groups.